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O'Quinn Black
02/25/2023 · Middle School

Are the scaffolds of eukaryotic chromosomes composed of histone or nonhistone chromosomal protems? I low has this been determined experimentally?

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Eukaryotic chromosomes are primarily composed of histone proteins, which are crucial for packaging DNA into chromatin. This has been confirmed through various experiments including electron microscopy, ChIP, mass spectrometry, biochemical analysis, and genetic studies. Nonhistone proteins are also present but do not form the primary scaffold.

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